In the univariate analysis, LVMI was significantly associated with 24-hour urinary aldosterone level, body mass index, body weight, log-transformed PAC, log-transformed PRA, log-transformed PAC-to-PRA ratio (ARR), systolic and diastolic blood pressure, gender, serum potassium level, the use of alpha-blocker, and the presence of adenoma (Table 3). Here, S100A6 is linked to adenoma.