Several pan mTOR (mTORC1/2) dual kinase inhibitors (AZD8055 and its related compound AZD2014 (Astra Zeneca), as well as INK128 (Intellikine) and OSI-027 (OSI Pharmaceuticals)) are currently in phase I/II studies on solid tumours and breast cancer or lymphoma[30-33]. This evidence concerns the gene MTOR and breast cancer.