She showed a little increase of serum glutamic oxaloacetic transaminase (AST) and of serum glutamic pyruvic transaminase (ALT) levels, approximately two times the upper limit of the normal range, platelet count (PLT) about 132,000/mm3, absence of splenomegaly, anti-HCV positivity and positive serum HCV-RNA, genotype 3a. This evidence concerns the gene GPT and Splenomegaly.