EGF and fibrosarcoma: Our data are in agreement with other studies showing a significant inhibition of Erk phosphorylation in human fibrosarcoma cells by resveratrol[24] and blockage of Erk phosphorylation, inhibition of the upstream kinases Raf and MEK, and suppression of the EGF or Ras-induced transformation of JB6Pt mouse skin epidermal cells by red wine extract[24].