MC4R and obesity due to melanocortin 4 receptor deficiency: These variants were FTO (fat mass and obesity associated) (rs9939609), GNPDA2 (glucosamine-6-phosphate deaminase 2) (rs10938397), KCTD15 (potassium channel tetramerisation domain containing 15) (rs11084753), MC4R (melanocortin-4 receptor) (rs17782313), MTCH2 (mitochondrial carrier 2) (rs10838738), NEGR1 (neuronal growth regulator 1) (rs2815752), TMEM18 (transmembrane protein 18) (rs6548238), and SH2B1 (SH2B adaptor protein 1) rs7498665).