IL7 and obesity due to melanocortin 4 receptor deficiency: In fact, a single administration of IL-7 was sufficient to decrease adipose tissue inflammation and to protect mice from obesity in three different models of experimentally induced obesity (i.e., monosodium glutamate-induced hypothalamic obesity [84], gold thioglucose-induced hypothalamic obesity (Wolowczuk I, unpublished data), and HF diet- (HFD-) induced obesity [82]).