CRP and adult-onset Still disease: Here, we report a patient with systemic flare of AOSD with no response to treatment with high-dose corticosteroids, immunosuppressants, and anti-IL6 receptor antibody, tocilizumab, and successfully treated with higher-dose soluble TNFα receptor agent, etanercept, in conjunction with the results of serum levels of C-reactive protein (CRP) and proinflammatory cytokines.