Besides colon cancer cells, HDAC inhibitory effects of SFN have been shown in various prostate epithelial cells—normal prostate epithelial cells (PrEC), benign hyperplasia (BPH1), and cancerous (LnCaP, PC-3) prostate epithelial cells [69, 70] as well as in different breast cancer cells [71]. The gene discussed is HDAC9; the disease is malignant colon neoplasm.