More importantly, BNC1 hypermethylation correlated with poorer patient survival in the HumanMethylation27 BeadChip cohort, where it represented a more significant prognostic marker for patient survival than tumor stage, grade or dimension, and in the HumanMethylation450 BeadChip cohort, where it was the only remaining statistically significant marker after tumor grade. Here, BNC1 is linked to neoplasm.