Recently, Ky et al.[23] showed that adding a more complex biomarker panel consisting of high-sensitivity C-reactive protein, myeloperoxidase, B-type natriuretic peptide, soluble fms-like tyrosine kinase receptor-1, troponin I, ST2, creatinine, and uric acid to the Seattle HF Model improves the predictive accuracy for 1-year all-cause death, with a C-statistic up to 0.8. The gene discussed is MPO; the disease is hydrops fetalis.