ST6GAL1 and neoplasm: Fig. 3D showed that in the group of mice bearing K562 tumors, tumor volumes with adriamycin treatment were lower than those without. But in the group of mice bearing K562/ST6GAL1 tumors, tumor volumes increased significantly even after adriamycin treatment. High expression level of ST6GalI in tumor cells of K562/ST6GAL1 was also validated by IHC staining, as shown in Fig. 3E.