Then, we attempted to find out the relationship between GLI1 and Cav-1 expression on HCC tissues from HCC patients undergoing hepatic resection by IHC and found that Cav-1 expression was significantly associated with GLI1 expression positively, which confirms the regulatory function of GLI1 on Cav-1 in HCC. The gene discussed is CAV1; the disease is hepatocellular carcinoma.