There are a growing body of studies about Cav-1 expression in cancer, and interestingly, it was found to be aberrantly increased in some kinds of malignances such as bladder cancer[7], esophagus carcinoma[8], T cell leukemia[9], and prostate cancer[10], whereas down-regulated in breast cancer[11], cervix cancer[12], lung cancer[13], sarcoma[14], ovarian cancer[15], thyroid follicular cancer[16] and colon cancer[17]. The gene discussed is CAV1; the disease is Familial prostate cancer.