The recent approval of SGN-35 (Adcetris), an anti-CD30 Auristatin ADC for the treatment of Hodgkin's lymphoma and Trastuzumab Emtansine (T-DM1), an anti-Her2/ErbB2 ADC for the treatment of malignant breast cancer, provides evidence of these improvements. The gene discussed is ERBB2; the disease is Hodgkins lymphoma.