H1-0 and autoimmune hepatitis: In addition to the involvement of Ab response against nuclear histone H1 in liver transplant tolerogenicity [17], anti-histone H1 Ab was found to be expressed spontaneously in sera during the recovery stage from Concanavalin A (Con A-) induced transient liver injury, suggesting the significance of anti-histone H1 Ab as a regulatory Ab (Abreg) for both protection and recovery from autoimmune hepatitis [18].