Febuxostat (Adenuric ▼), 2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methylthiazole-5-carboxylic acid is a nonpurine selective inhibitor of xanthine oxidase (XO) used for the treatment of hyperuricemia and gout and was approved in the USA. The gene discussed is XDH; the disease is gout.