The frequencies of Tim-1+, CD4+Tim-1+, and CD8+Tim-1+ cells were analyzed in cells from lymph nodes (LN), spleen (SP), and PBMCs of normal healthy (Nor) and BDN (HSV-1 was inoculated but no symptoms) mice and compared with those in BD mice by FACS. The gene discussed is HAVCR1; the disease is Behcet disease.