CD4 and Behcet disease: After 1 week, Treg cells increased slightly in siTim-4 treated BD mice compared with those in the NC treated group (NC versus siTim-4: CD4+CD25+, 5.82 ± 2.01% versus 6.84 ± 2.03%, P = 0.45, n = 5; CD4+Foxp3+, 4.64 ± 1.9% versus 5.82 ± 2.4%, P = 0.41, n = 5; Treg, 3.28 ± 1.57% versus 4.08 ± 1.73%, P = 0.47, n = 5).