CD8A and Behcet disease: In LN, the frequencies of Tim-1+, CD4+Tim-1+, and CD8+Tim-1+ cells in BD mice were significantly lower than those in BDN mice (BDN versus BD (%): Tim-1+, 20.1 ± 11.5 (n = 12) versus 11.1 ± 6.7 (n = 12), P = 0.01; CD4+Tim-1+, 3.4 ± 1.9 (n = 9) versus 2.2 ± 1.6 (n = 9), P = 0.09; CD8+Tim-1+, 1.9 ± 1.1 (n = 9) versus 1.1 ± 0.6 (n = 9), P = 0.04) (Figure 1(a)).