TNFRSF6B and rheumatoid arthritis: DcR3 is rarely detectable in serum of healthy subjects, whereas its expression is increased in that of various autoimmune and inflammatory diseases such as IBD [67, 86], SLE [78], RA [60], PBC [77], silicosis [87], viral infections [82], renal failure [88], and atopic dermatitis [89] as well as cancer [90].