Our data indicated that the target genes of radiation-response miRNAs were frequently significantly enriched in several cancer- or radiation-related pathways, including the mitogen-activated protein kinase (MAPK), ErbB, p53, Wnt, transforming growth factor-β (TGF-β) and mTOR signaling pathways with an FDR <0.05 (Table III). Here, TP53 is linked to cancer.