Protein restricted diets at least <0.8–1 g/kg/day is only recommended in Type 1 DM, showing reduction in hyperglycemia and decreased insulin requirements. Anthropometric parameters were preserved. LPD (using specific enteral supplements) should be used by patients in the early stages of diabetic nephropathy to slow progression of renal failure. No specific protein intake levels are prescribed. This evidence concerns the gene INS and kidney failure.