In addition to IgE-mediated cow’s milk allergy there is increasing awareness that early consumption of cow’s milk may be a risk for the development of autoimmune diseases such as celiac disease, Crohn’s disease, Behçets disease, MS, mild rheumatoid arthritis in rabbits, and type 1 diabetes in humans [20,21,22,23,24,25]. Here, IGHE is linked to autoimmune disease.