The consistent significant correlations of these genes to IFN from the low levels observed in HD (Figure 4, right panels) to aberrantly high pathogenic levels of IFN in SLE patient visits (Figure 4, left panels) was indicative of a normal intrinsic response of ADAR, CCL2, and CXCL10 to IFN production. Here, CXCL10 is linked to systemic lupus erythematosus.