STAT1 and systemic lupus erythematosus: Similarly, for SLE patients with increasing STAT1 by at least 50% between the first and second visit (n = 25; P <0.0001, Figure 3B), significant increases were observed for IFN score (P = 0.027), CCL2 (P <0.0001), CXCL10 (P = 0.0003), and miR-146a (P = 0.0078).