ALB and gout: The objective of this multicenter, double-blind, randomized placebo-controlled study was to evaluate the effect of topiroxostat in reducing the serum urate level, and to improve the estimated glomerular filtration rate (eGFR), urinary albumin-to-creatinine ratio (ACR), blood pressure, and serum adiponectin levels in hyperuricemic patients with renal impairment, with or without gout.