To gain more detailed insights into the function of the GATA2 gene in prostate cancer metastasis, we first identified a core set of 970 GATA2-relevant genes that were both significantly differentially expressed after GATA2 gene silencing in LNCaP cells (Student's t-test; FDR < 0.05 and FC > 1.5) and whose expressions significantly correlated with those of the GATA2 gene in the MSKCC Prostate Oncogenome Project (Pearson's correlation; correlation coefficient > 0.30, FDR < 0.01). Here, GATA2 is linked to Familial prostate cancer.