As well, significant main effect of ischemia (F(3,36) = 9.71, P <0.05) and CX3CR1 (F(3,36) = 10.23, P <0.05) were seen in error rate wherein ischemic rats and sham animals with CX3CR1 deficiency made more errors in the delayed non-matching-to-sample task when compared to the sham control group; however, ischemic rats that received the CX3CR1 siRNA showed the worst performance overall (Figure 6E). Here, CX3CR1 is linked to ischemia.