MFGE8 and neoplasm: The approach used by Fens et al. [41] is completely different: based on the fact that lactadherin behaves as an opsonin for the rapid clearance of apoptotic cells and taking into account that tumor angiogenic endothelium expresses integrins to which lactadherin attaches, this study demonstrates that tumor angiogenic endothelial cells have indeed the ability to phagocytose lactadherin-opsonized large particles, aged erythrocytes and apoptotic cells.