Moreover, high expression of GOLPH3 has been shown to be associated with poor prognosis in breast cancer, esophageal squamous cell carcinoma (ESCC), oral tongue cancer, gastric cancer, prostate cancer, glioblastoma multiforme, gliomas, and rhabdomyosarcoma[11-18] . The gene discussed is GOLPH3; the disease is esophageal squamous cell carcinoma.