Presence of diabetes mellitus (1.52 ± 0.42 ng/ml vs. 1.43 ± 0.35 ng/ml; p > 0.05), hypertension (1.45 ± 0.51 ng/ml vs. 1.47 ± 0.15 ng/ml, p > 0.05) and hyperlipidemia (1.37 ± 0.77 ng/ml vs. 1.50 ± 0.38 ng/ml, p > 0.05) did not differ apelin-36 levels also. This evidence concerns the gene APLN and hyperlipidemia.