C/EBPβ is a critical regulator of acute-phase pro-inflammatory genes involved in host response to infections[55,56] and is implicated in the release of inflammatory and adhesion factors such as IL-6, TNFα, CD40, ICAM-1 and bioactive tachykinins responsible for neuroinflammation and tissue repair in the central nervous system[57-62]. Here, ICAM1 is linked to infection.