In this group of anti-SSA negative pSS patients, the frequency of the different tests was: 56.7% for ANA ≥1:320; 40.0% for ANA ≥1:640; 20.0% for IgM-RF; 10.0% for ACR 2012 criteria serological item (anti-SSA/B or (ANA ≥1:320 + positive RF)); 10.0% for gammaglobulins ≥14 g/l; 16.7% for IgG ≥14 g/l; and 40.0% for B-cell ratio ≥5. This evidence concerns the gene CD40LG and peeling skin syndrome.