In addition, an anti-human polyclonal PTPN22 antibody, which was raised against S306-S684 of PTPN22.1 and should recognize all isoforms, detected one dominant broad protein band centering around 110 kD and several smaller protein species in Jurkat human T cells but not in HT-29 adenocarcinoma cells, which do not express PTPN22 (Figure 1D and [13]). The gene discussed is PTPN22; the disease is adenocarcinoma.