PPARG and cerebral malaria: Notably, PPARγ has been reported to be one of only two genes in a cerebral malaria-resistance locus identified using a genome-wide analysis of 32 different inbred mouse lines (Bopp et al., 2010) and modulation of the inflammatory response to P. berghi infection by an antagonist of this gene has greatly enhanced the survival rates in mice (Serghides et al., 2009).