Correlations restricted to patients with COPD alone show that the number of IFNγRI+ cells correlated with the number of IL-27+ (R=0.42, p=0.036) and IL-27R+ (R=0.51, p=0.014) cells in the bronchial submucosa (figure 4A,B). The gene discussed is IL27RA; the disease is chronic obstructive pulmonary disease.