The number of IL-37+ (figure 2) and NALP7+ (see online supplementary figure E3) cells was higher in patients with severe stable COPD compared with control smokers (p=0.054 and p=0.0015 respectively) and in patients with mild/moderate stable COPD in comparison with control smokers (p=0.008 and p=0.0043 respectively). The gene discussed is IL37; the disease is chronic obstructive pulmonary disease.