Besides, Yadanzi may intercept NSCLC tumorgenesis by disturbing a number of pathways like cell cycle via CDK6, MMP7 and FHIT, PPAR signaling pathway via RXRA, PDPK1 and MMP1, calcium signaling pathway via PRKCB, and etc. These proteins or pathways were peripheral of the above two routes. Here, FHIT is linked to non-small cell lung carcinoma.