These “weak” ingredient-target interactions are involved in different cellular processes like metabolisms (nitrogen metabolism, retinol metabolism, drug metabolism, and etc) and signal transductions (Wnt signaling pathway, insulin signaling pathway, MAPK signaling pathway, and etc), forming an incredibly complex molecular network that more or less connects with NSCLC development and spread as well as other pathogenesis. Here, INS is linked to non-small cell lung carcinoma.