In our patient microscopic examination of the specimen obtained by core biopsy revealed the presence of a poorly differentiated carcinoma with a strong cytoplasmatic positivity for Cytokeratin 19 [12], and negative staining for thyroglobulin and TTF-1 [13], thus favouring the diagnosis of metastatic tumour over a primary thyroid cancer. This evidence concerns the gene TG and metastatic neoplasm.