KRAS and colon adenocarcinoma: Iliopoulos et al. reported that the expression of miR-193a is inversely correlated with K-RAS and plasminogen activator urokinase (PLAU) expression in human colon adenocarcinomas, and that miR-193 expression inhibits tumorigenicity and invasiveness by directly targeting K-RAS and PLAU, respectively (Iliopoulos et al., 2011).