An elegant paper by Yotnda et al. identified a BCR/ABL1 junctional nonapeptide (SSKALQRPV) that binds to human leukocyte antigen (HLA)-A2.1 and elicits specific CTL responses in vitro in blood from healthy donors and CML patients. The gene discussed is BCR; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.