CCN4 and invasive breast carcinoma: The objective of this retrospective study of invasive breast cancer was three-fold: 1) to determine whether the gene signature associated with type 1 cell-mediated cytotoxic immunity was correlated with overall survival, 2) to determine whether WISP1 expression is increased in invasive breast cancer, and 3) to determine whether a pattern of gene expression consistent with inhibition of IL12 signaling axis correlates with WISP1 expression.