There are currently three VEGF inhibitors approved for the treatment of wet AMD in Germany: pegaptanib (Macugen®, Pfizer, New York City, NY, US), ranibizumab (Lucentis®, Novartis Pharmaceuticals, Basel, Switzerland), and recently aflibercept (Eyelea®, BayerPharma AG, Berlin, Germany). Here, VEGFA is linked to wet macular degeneration.