Treatment with the extract has shown increased peak urine flow, and decreased nocturia, without increasing serum prostate-specific antigen (PSA) levels.[4] In a pilot trial, we could show that saw palmetto also had a positive effect on concomitant sexual dysfunctions in BPH patients.[5] The dose recommended for a lipophilic saw palmetto extract is 320 mg daily administered once daily. This evidence concerns the gene KLK3 and sexual dysfunction.