TGFB3 and arrhythmogenic right ventricular cardiomyopathy: Although Beffagna et al. [26] demonstrated a clear cosegregation of ARVD/C type 1 with the mutation in the 5′ UTR region of the TGFβ3 gene, one may question whether TGFβ3 overexpression is the actual molecular basis of ARVD/C type 1.