Another RBP, hnRNP-A1, is also upregulated in CML-BC and has been shown to bind pri-miR-17-92 [43], which might attempt to explain a lack of miR-17-92 expression in CML-BC, as described previously. The gene discussed is HNRNPA1; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.