In the reported study, we performed genetic and molecular analysis of four lymphoma cases with non-IG translocations of FOXP1 and compared these with cases harboring t(3;14)(p13;q32)/IGH-FOXP1 and DLBCLs with a strong expression of FOXP1 and with no apparent structural aberrations of the gene (FOXP1-positive DLBCL). This evidence concerns the gene FOXP1 and diffuse large B-cell lymphoma.