Since proton leak respiration is one of the major differences in respiratory parameters between the two AD LCL subgroups, we measured UCP2 content by western blots in a subset of LCLs from both the AD-A (N = 4) and AD-N (N = 6) subgroups to determine whether UCP2 protein content differed between the two AD subgroups at baseline (i.e., without exposure to DMNQ). This evidence concerns the gene UCP2 and Alzheimer disease.