By using the web-based prediction tool, doRiNA [38], we found that miR-106b-5p (one of the miR-106b-25 cluster) can target an X-linked inhibitor of apoptosis protein (XIAP), which has been reported to exhibit elevated expression levels in hepatocellular carcinoma (HCC) and promote cell survival, metastasis and tumor recurrence [39]. The gene discussed is XIAP; the disease is hepatocellular carcinoma.