Because the SDF-1/CXCR4/CXCR7 axis plays a critical role in cancer development, progress, metastasis and recurrence, we hypothesize that SDF-1 and its receptors CXCR4 and CXCR7 might also be connected with the outcome of treatment of endometrial cancerpatients. The gene discussed is CXCL12; the disease is cancer.