We have evaluated the expression of SDF-1, CXCR4 and CXCR7 in the primary tumor cells.The expression of SDF-1 was found in 90% cases, the expression ofCXCR4 and CXCR7was found in 100%of all cases of endometrial cancer (Figure 1).Analysis of expression evaluated in adjacent normal tissue revealed very low expression (IRS  = 1) of CXCR4 in normal endometrium. This evidence concerns the gene CXCR4 and endometrial cancer.