APC and neoplasm: There was no significant difference in the prevalence of somatic mutations other than c.3924_3925insA in tumours with LOH as compared to those without LOH, with 10 of 19 tumours (53%) with APC LOH also demonstrating at least one somatic mutation, while 21 of 56 (37.5%) tumours without APC LOH demonstrated at least one somatic change, p = 0.29.