FIS1 and acute myeloid leukemia: AML patients had higher PDCD7 and lower KLRF1 expression levels than those of non-malignant controls (P = 0.047, P = 0.001, Fig. 1), and patients with high FIS1 and APP expression were more likely to be classified as FAB M0/M1 subtype (P = 0.038, P = 0.018, Fig. 2), however, other targets had no similar results (P>0.05).