[6]. Zinc is involved in the synthesis, storage, and secretion of monomeric insulin, as well as conversion to a dimeric form for storage and secretion as crystalline insulin [7], [8]. Zinc is essential in insulin action and carbohydrate metabolism [9]. Oxidative stress also plays an important role in the pathogenesis of diabetes and its complications, and zinc is a structural component of key antioxidant enzymes such as superoxide dismutase, which is vital for intra- and extracellular antioxidant defence [10]. This evidence concerns the gene INS and diabetes mellitus.