We did not find associations of LpPLA2 mass levels with lacunar strokes, arising from lipohyalinosis of small perforating arteries, which are generally considered to be related to hypertension and diabetes, or with cardioembolic stroke, related to the formation of thrombin-rich clots that form in the heart, often in the presence of atrial fibrillation. The gene discussed is PLA2G7; the disease is cardioembolic stroke.