In addition, histone deacetylase inhibitors (HDACi), a class of compounds that can induce cancer cell growth arrest and cell death by altering the acetylation status of both histone and non-histone proteins, can enhance the activity of FLT3 inhibitors on AML cell apoptosis [24], [25], [26]. The gene discussed is FLT3; the disease is acute myeloid leukemia.